LYME CARDITIS
The purpose of this study was to determine if oxygen/ozone therapy affected Lyme
disease caused by the spirochete, Borrelia Burgdorferi.
The spirochete, Borrelia Burdorferi is a microaerophilic organism carried by the
deer tick (Ixodid) and transferred to humans and other mammals by its bite.
Symptoms often are a bulls eye rash and erythema migrans. Other symptoms may
include pain in joints and muscles, sore throat, fever, swollen glands and
mental fogginess. If not diagnosed within one month or two months, the disease
may become a chronic infection. At that point of time it becomes sequestrated in
fibroblasts and other cells which, in turn appear to protect it against the
effective treatment by all known antibiotics so far tested. The disease is
difficult to diagnose without serological findings and requires the skill of a
highly qualified physician, experienced in treating this disease.
Lyme disease is caused by a tick-borne spirochete (Borrelia burgdorferi). It
usually begins during the summer months with a characteristic rash (erythema
chronicum migrans), followed in weeks to months by neurological, joint, or
cardiac involvement. Some clinical manifestation may persist for
years.
About 10 percent of patients with Lyme disease develop evidence of transient
cardiac involvement, the most common manifestation being variable degrees of
atrioventricular block at the level of the atrioventricular node. Syncope due to
complete heart block is frequent with cardiac involvement because often there is
an associated depression of ventricular escape rhythms. Ventricular tachycardia
occurs uncommonly. Diffuse ST segment and T wave abnormalities and transient,
usually asymptomic, left ventricular dysfunction may be found in some patients,
although cardiomegaly or symptoms of congestive heart failure are rare. A
positive gallium or indium antimyosin antibody scan may point to suspected
cardiac involvement in this disease. The demonstration of spirochetes in
myocardial biopsies of some patients with Lyme carditis suggests that the
cardiac manifestations are due to a direct toxic effect, although there is
speculation that immune-mediated mechanisms may be involved as well.
The value of specific therapy in Lyme carditis remains uncertain, and even
without therapy the disease usually is self-limited with complete recovery the
rule. Nevertheless, it is thought that treating the early manifestations of the
disease may prevent development of late complications. Patients with
second-degree or complete heart block should be hospitalized and undergo
continuous ECG monitoring. Temporary transvenous pacing may be required for up
to a week or longer in patients with high-grade block. Although the efficacy of
antibiotics is not established, they are utilized routinely in Lyme carditis.
Intravenous antibiotics (ceftriaxone, 2 gm, or penicillin G, 20 million units
daily for 14 days) are suggested, although oral antibiotics (doxycycline, 100 mg
twice daily, or amoxicillin, 500 mg three times daily for 14 to 21 days) may be
used when there is only mild cardiac involvement (first-degree
atrioventricular block of less than 40 milliseconds duration). Whether
anti-inflammatory agents (salicylates, corticosteroids) can ameliorate heart
block is not clear.
RELAPSING FEVER
Many infections are currently observed in Ethiopia. During pandemics, mortality
may be particularly high, reaching 70 percent, although sporadic cases are often
more benign. Cardiac involvement is said to be a common complication and is
often implicated as a cause of death, although one report involving 63 children
did not find evidence of cardiac involvement. Atrioventricular conduction
defects occur frequently and may be responsible for sudden death, although
tachyarrhythmia’s have also been implicated. Numerous petechiae are observed
with a diffuse histiocytic interstitial inflitrate, particularly around small
arterioles in the left ventricle.
SYPHILIS
Aortitis is the most common manifestation of luetic involvement of the
cardiovascular system. Aortic regurgitation and coronary ostial narrowing are
associated findings. Syphilitic involvement of the myocardium itself in the form
of gumma formation is uncommon and usually unsuspected clinically . Involvement
of the base of the interventricular septum may result in damage to the
conduction system and atrioventicular block. In one case a ruptured left
ventricular aneurysm was found as a result of syphilitic endarteritis.
FUNGAL INFECTIONS OF THE HEART
Cardiac fungal infections occur most frequently in patients with malignant
disease and/or those receiving chemotherapy, corticosteroids, radiation, or
immunosuppressive therapy. Cardiac surgery, intravenous drug abuse, and
infection with HIV are also predisposing factors for fungal cardiac involvement;
namely
CLINICAL MANIFESTATIONS
These include fever, muscle pains, sweating, hepatosplenomegaly, myocarditis
with congestive heart failure, pericardial effusion, and, occasionally,
meningoencephalitis. Most patients recover, and their symptoms resolve over
several months. Young children most commonly develop clinical acute disease and
generally are more seriously ill than adults.
My point is Recirculatory Haemoperfusion™ is the only treatment for the above,
without any side effects. There are many patients in my research whose Lyme
disease treatment resulted in complications due to JARISH-HERXHEIMER REACTION
(JRH)."
For Example: Lyme patients who WERE treated with amoxicillin became
very ill after the first dose of antibiotics. They were hypertensive,
their temperature shot up, they experienced rigor, some were hypotensive and we
started normal saline. This is a systemic illness. The JHR was first noted in
association with antibiotic therapy for neurosyphlis. Thus, the administration
of antibiotics may bring about JHR.
The patients who were on RHP™ had no JRH and their conditions resolved.
All Lyme symptoms and complications abated and clinical testing showed all signs
of Lyme infestation were gone from their systems. AND THEIR CONDITIONS
RESOLVED.